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CELLO-1: A Phase 1b/2 Open-Label Study Evaluating Tazemetostat in Combination With Enzalutamide or Abiraterone/Prednisone in Chemotherapy Naive Subjects With Metastatic Castration-Resistant Prostate Cancer

Trial Profile

CELLO-1: A Phase 1b/2 Open-Label Study Evaluating Tazemetostat in Combination With Enzalutamide or Abiraterone/Prednisone in Chemotherapy Naive Subjects With Metastatic Castration-Resistant Prostate Cancer

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 11 Dec 2024

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At a glance

  • Drugs Abiraterone (Primary) ; Abiraterone acetate (Primary) ; Enzalutamide (Primary) ; Prednisone (Primary) ; Tazemetostat (Primary)
  • Indications Adenocarcinoma; Neuroendocrine tumours; Prostate cancer
  • Focus Adverse reactions; Proof of concept; Therapeutic Use
  • Acronyms CELLO-1
  • Sponsors Epizyme; Ipsen Biopharmaceuticals

Most Recent Events

  • 09 Dec 2024 Status changed from active, no longer recruiting to discontinued.
  • 31 Oct 2024 Planned End Date changed from 30 Sep 2024 to 8 Nov 2024.
  • 31 Oct 2024 Planned primary completion date changed from 30 Sep 2024 to 8 Nov 2024.

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