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STELLAR: A phase II, randomiSed study of CHOP-R in combination with acalabruTinib comparEd to CHOP-R in patients with newLy diagnosed Richter's Syndrome (RS) and a pLAtfoRm for initial investigations into activity of novel treatments in relapsed/refractory and newly diagnosed RS

Trial Profile

STELLAR: A phase II, randomiSed study of CHOP-R in combination with acalabruTinib comparEd to CHOP-R in patients with newLy diagnosed Richter's Syndrome (RS) and a pLAtfoRm for initial investigations into activity of novel treatments in relapsed/refractory and newly diagnosed RS

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 16 May 2024

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At a glance

  • Drugs Acalabrutinib (Primary) ; Cyclophosphamide; Doxorubicin; Prednisolone; Rituximab; Vincristine
  • Indications Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma; Richter's syndrome
  • Focus Therapeutic Use
  • Acronyms STELLAR
  • Most Recent Events

    • 15 Jun 2023 Results presented at the 28th Congress of the European Haematology Association
    • 05 Jan 2023 Planned End Date changed from 1 Dec 2024 to 31 May 2027.
    • 05 Jan 2023 Planned primary completion date changed from 1 Apr 2024 to 31 Oct 2025.

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