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A Randomised, Crossover study to evluated the Drug-Drug Interactions and the impact of ketoconazole on the pharmacokinetics of rivaroxaban, apixaban and edoxaban administered as microdoses in Healthy volunteers

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Trial Profile

A Randomised, Crossover study to evluated the Drug-Drug Interactions and the impact of ketoconazole on the pharmacokinetics of rivaroxaban, apixaban and edoxaban administered as microdoses in Healthy volunteers

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 07 Mar 2019

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At a glance

  • Drugs Apixaban (Primary) ; Edoxaban (Primary) ; Rivaroxaban (Primary) ; Ketoconazole
  • Indications Acute coronary syndromes; Cardiovascular disorders; Coronary thrombosis; Deep vein thrombosis; Embolism; Heart failure; Heparin-induced thrombocytopenia and thrombosis syndrome; Peripheral arterial disorders; Pulmonary embolism; Stroke; Thromboembolism; Thrombosis; Venous thromboembolism
  • Focus Pharmacokinetics

    • Most Recent Events

    • 07 Mar 2019 New trial record
    • 04 Mar 2019 Results published in the Clinical Pharmacokinetics

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