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A Phase I Trial to Study Single and Multiple Ascending Doses of Oral BCX9930 in Healthy Subjects

Trial Profile

A Phase I Trial to Study Single and Multiple Ascending Doses of Oral BCX9930 in Healthy Subjects

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 22 Dec 2022

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At a glance

  • Drugs Pelecopan (Primary)
  • Indications Paroxysmal nocturnal haemoglobinuria
  • Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics
  • Sponsors BioCryst Pharmaceuticals

Most Recent Events

  • 15 Dec 2022 According to a BioCryst Pharmaceuticals media release, based on new competitive data recently presented at the American Society of Hematology (ASH) annual meeting, the company no longer believes that BCX9930 would be commercially competitive, and is discontinuing the development of BCX9930. This decision allows the company to fully focus its complement inhibitor development efforts on BCX10013
  • 15 Dec 2022 Status changed from recruiting to discontinued as per BioCryst Pharmaceuticals media release
  • 12 Jan 2020 According to a BioCryst Pharmaceuticals media release, the company has completed an additional MAD cohort with 50 mg of oral BCX9930 or placebo administered every 12 hours for 14 days, with vaccination instead of an antibiotic.

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