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A phase I/II clinical trial of ICTCAR014 in patients with relapsed or refractory non-Hodgkin lymphoma (NHL), including patients whose tumors are PD-L1 positive.

Trial Profile

A phase I/II clinical trial of ICTCAR014 in patients with relapsed or refractory non-Hodgkin lymphoma (NHL), including patients whose tumors are PD-L1 positive.

Status: Planning
Phase of Trial: Phase I/II

Latest Information Update: 09 Dec 2019

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At a glance

  • Drugs ICTCAR 014 (Primary)
  • Indications Non-Hodgkin's lymphoma
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 04 Dec 2019 According to an Innovative Cellular Therapeutics media release, this trial is expected to begin in the first part of 2020. Dr. David L. Porter of the Abramson Cancer Center of the University of Pennsylvania will be the Lead Principal Investigator for the clinical trial.
  • 04 Dec 2019 According to an Innovative Cellular Therapeutics media release, the U.S. Food and Drug Administration (FDA) has cleared the Investigational New Drug (IND) application for ICTCAR014.
  • 19 Mar 2019 According to an Innovative Cellular Therapeutics media release, company has received positive feedback from the U.S. Food and Drug Administration during the pre-IND meeting and plan to submit an IND for ICTCAR014 to the FDA in the second quarter of 2019

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