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A Phase I Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor (CDAi) With Oral Decitabine in Subjects With Solid Tumors

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Trial Profile

A Phase I Dose-Escalation Study of E7727, an Oral Cytidine Deaminase Inhibitor (CDAi) With Oral Decitabine in Subjects With Solid Tumors

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Cedazuridine (Primary) ; Decitabine (Primary)
  • Indications Solid tumours
  • Focus Adverse reactions

    • Most Recent Events

    • 04 Mar 2025 Planned number of patients changed from 30 to 35.
    • 04 Mar 2025 Planned End Date changed from 1 Dec 2025 to 1 Dec 2026.
    • 04 Mar 2025 Planned primary completion date changed from 2 Jun 2025 to 2 Jan 2026.

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