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International, Multicentre, Parallel-group, Randomised, Double-blind, Placebo-controlled, Phase III Study Evaluating the Effect of Dapagliflozin on Exercise Capacity in Heart Failure Patients With Preserved Ejection Fraction

Trial Profile

International, Multicentre, Parallel-group, Randomised, Double-blind, Placebo-controlled, Phase III Study Evaluating the Effect of Dapagliflozin on Exercise Capacity in Heart Failure Patients With Preserved Ejection Fraction

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 06 Nov 2024

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At a glance

  • Drugs Dapagliflozin (Primary)
  • Indications Chronic heart failure
  • Focus Registrational; Therapeutic Use
  • Acronyms DETERMINE-Preserved
  • Sponsors AstraZeneca; AstraZeneca AB; AstraZeneca KK

Most Recent Events

  • 01 Oct 2024 Results of exploratory analysis of DETERMINE trials (NCT03877237 and NCT03877224) assessing effect of dapagliflozin on accelerometer-based measures of physical activity in patients with heart failure, published in the Circulation: Heart Failure.
  • 07 Dec 2023 Results from NCT03877237 and NCT03877224 assessing Effect of Dapagliflozin Versus Placebo on Symptoms and 6-Minute Walk Distance in Patients With Heart Failure, published in the Circulation
  • 04 Oct 2020 This trial has been completed in Sweden, according to European Clinical Trials Database record.

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