A Randomized, Phase 3, Open-Label Trial Comparing the Effect of LY3298176 Versus Titrated Insulin Degludec on Glycemic Control in Patients With Type 2 Diabetes
Latest Information Update: 23 May 2024
At a glance
- Drugs Tirzepatide (Primary) ; Insulin degludec
- Indications Type 2 diabetes mellitus
- Focus Registrational; Therapeutic Use
- Acronyms SURPASS-3
- Sponsors Eli Lilly and Company
Most Recent Events
- 23 May 2024 Results describing the overall fat distribution patterns independent of body mass index (BMI) in participants with type 2 diabetes (T2D) in the SURPASS-3 MRI substudy by comparison with sex- and BMI-matched virtual control groups (VCGs) derived from the UK Biobank imaging study at baseline and Week 52, published in the Diabetes, Obesity and Metabolism
- 10 Apr 2024 According to a AMRA Medical media release, an exploratory analysis published in Diabetes, Obesity and Metabolism using data from SURPASS-3 MRI study, shows significant reduction of both visceral- and liver fat z-scores, and a shift towards a more balanced fat distribution pattern with tirzepatide treatment.
- 25 Jan 2024 Results assessing the evaluate gastrointestinal adverse events (AEs) and the impact of nausea, vomiting or diarrhoea (N/V/D) and any gastrointestinal (GI) AEs overall on weight change with tirzepatide from SURPASS 1-5 Trials, published in the Diabetes, Obesity and Metabolism