An Open-label, Safety and Tolerability Phase 1b Trial of CAN04, a Fully Humanized Anti-IL1RAP Monoclonal Antibody, in Combination With Pembrolizumab in Subjects With Solid Tumors Progressing on PD-1/PD-L1 Inhibitor-containing Regimens
Latest Information Update: 03 Jan 2025
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At a glance
- Drugs Carboplatin (Primary) ; Nadunolimab (Primary) ; Pembrolizumab (Primary) ; Pemetrexed (Primary)
- Indications Adenocarcinoma; Bladder cancer; Head and neck cancer; Malignant melanoma; Non-small cell lung cancer; Urogenital cancer
- Focus Adverse reactions
- Acronyms CIRIFOUR
- Sponsors Cantargia
- 13 Jul 2023 Status changed from active, no longer recruiting to completed.
- 09 Nov 2022 Status changed from recruiting to active, no longer recruiting.
- 19 Oct 2022 As per CT.gov Outcome Measures, Arms and Interventions, Study Status, Study Identification, Eligibility, Study Design and Study Description has been amended