Trial Profile

A randomised, placebo-controlled, double-blind trial of the antidepressant efficacy of a novel CNS-penetrant P2X7 receptor antagonist, JNJ-54175446, in people with major depressive disorder, an incomplete response to monoaminergic antidepressant drugs, and a biomarker profile predictive of active P2X7 signalling

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 23 Feb 2024

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At a glance

20 Jun 2022 Recruitment completion is expected on 10 Jun 2022, according to ISRCTN: Current Controlled Trials.
20 Jun 2022 Status changed from recruiting to active, no longer recruiting.
10 May 2022 Planned End Date changed from 30 Jun 2022 to 30 Jun 2024.

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