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A Phase 1/2 Single Arm Open-Label Clinical Trial of Gavocabtagene Autoleucel (Gavo-cel) in Patients With Advanced Mesothelin-Expressing Cancer

Trial Profile

A Phase 1/2 Single Arm Open-Label Clinical Trial of Gavocabtagene Autoleucel (Gavo-cel) in Patients With Advanced Mesothelin-Expressing Cancer

Status: Active, no longer recruiting
Phase of Trial: Phase I/II

Latest Information Update: 13 Mar 2024

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At a glance

  • Drugs Gavocabtagene autoleucel (Primary) ; Ipilimumab (Primary) ; Nivolumab (Primary) ; Anetumab ravtansine; CAR-T cell therapies; Cyclophosphamide; Fludarabine
  • Indications Adenocarcinoma; Cholangiocarcinoma; Malignant-mesothelioma; Non-small cell lung cancer; Ovarian cancer; Peritoneal cancer; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors TCR2 Therapeutics

Most Recent Events

  • 05 Mar 2024 Planned End Date changed from 1 Apr 2026 to 2 Nov 2028.
  • 05 Mar 2024 Planned primary completion date changed from 1 Jul 2024 to 2 Nov 2028.
  • 05 Mar 2024 Status changed from recruiting to active, no longer recruiting.

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