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An Open-label, 2-Period, Fixed-sequence, Phase 1 Study in Healthy Volunteers to Evaluate the Effect of Itraconazole, a Potent CYP3A Inhibitor, on the Pharmacokinetics of Olinciguat (IW-1701)

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Trial Profile

An Open-label, 2-Period, Fixed-sequence, Phase 1 Study in Healthy Volunteers to Evaluate the Effect of Itraconazole, a Potent CYP3A Inhibitor, on the Pharmacokinetics of Olinciguat (IW-1701)

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs Olinciguat (Primary) ; Itraconazole
  • Indications Sickle cell anaemia
  • Focus Pharmacokinetics
  • Sponsors Cyclerion Therapeutics

    • Most Recent Events

    • 11 Jul 2019 Status changed from active, no longer recruiting to completed.
    • 29 May 2019 Status changed from recruiting to active, no longer recruiting.
    • 18 Apr 2019 Status changed from not yet recruiting to recruiting.

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