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A Multicenter, Open-Label, First-in-Human, Phase 1b/2a Trial of EO2401, a Novel Multipeptide Therapeutic Vaccine, With and Without Check Point Inhibitor, Following Standard Treatment in Patients With Progressive Glioblastoma

Trial Profile

A Multicenter, Open-Label, First-in-Human, Phase 1b/2a Trial of EO2401, a Novel Multipeptide Therapeutic Vaccine, With and Without Check Point Inhibitor, Following Standard Treatment in Patients With Progressive Glioblastoma

Status: Completed
Phase of Trial: Phase I/II

Latest Information Update: 14 Nov 2024

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At a glance

  • Drugs Bevacizumab (Primary) ; EO 2401 (Primary) ; Nivolumab (Primary)
  • Indications Brain cancer; Glioblastoma
  • Focus Adverse reactions; First in man; Proof of concept
  • Acronyms ROSALIE
  • Sponsors Enterome

Most Recent Events

  • 11 Nov 2024 Status changed from active, no longer recruiting to completed.
  • 26 Apr 2024 This trial has been completed in Germany (4 Mar 2024).
  • 17 Apr 2024 According to an Enterome Media Release, data from this study published in Journal of Clinical Oncology, Journal for ImmunoTherapy of Cancer 2022, Annals of Oncology 2022.

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