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A Multi-center, Randomized, Open-label, Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria and Active Hemolysis

Trial Profile

A Multi-center, Randomized, Open-label, Efficacy, Safety, Pharmacokinetics and Pharmacodynamics Study, Assessing Multiple LNP023 Doses in Adult Patients With Paroxysmal Nocturnal Hemoglobinuria and Active Hemolysis

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 21 Dec 2023

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At a glance

  • Drugs Iptacopan (Primary)
  • Indications Paroxysmal nocturnal haemoglobinuria
  • Focus Therapeutic Use
  • Sponsors Novartis Pharmaceuticals
  • Most Recent Events

    • 13 Dec 2022 Results of integrated analysis of X2201 and X2204 studies evaluating dose exposure response relationships of biomarkers and efficacy measures to support dose selection for iptacopan presented at the 64th American Society of Hematology Annual Meeting and Exposition
    • 05 Apr 2022 Status changed from active, no longer recruiting to completed.
    • 14 Dec 2021 Results presented at the 63rd American Society of Hematology Annual Meeting and Exposition

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