Trial Profile

A randomized, placebo-controlled phase 2 clinical study of PBI-4050 in patients with Nonalcoholic steatohepatitis (NASH)

Status: Discontinued

Phase of Trial: Phase II

Latest Information Update: 26 Jul 2022

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At a glance

21 Jul 2022 According to Liminal BioSciences media release, the company has discontinued development of fezagepras based on results from the Phase 1a single ascending dose ("SAD") clinical trial, which indicated fezagepras was significantly inferior compared to Sodium Phenylbutyrate as a nitrogen scavenger. The recommendation to stop the development program for fezagepras was not based on safety concerns.
21 Jul 2022 Status changed from planning to discontinued, according to a Liminal BioSciences media release.
05 Apr 2019 New trial record

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