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A Randomized, Open-label Trial Comparing Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBeAg-positive Advanced Stage Hepatocellular Carcinoma (VICI-5)

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Trial Profile

A Randomized, Open-label Trial Comparing Immune Checkpoint Therapy vs Target Therapy in Reducing Serum HBsAg Levels in Patients With HBeAg-positive Advanced Stage Hepatocellular Carcinoma (VICI-5)

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 01 Mar 2024

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At a glance

  • Drugs Cabozantinib (Primary) ; Durvalumab (Primary) ; Lenvatinib (Primary) ; Regorafenib (Primary) ; Sorafenib (Primary)
  • Indications Liver cancer
  • Focus Biomarker; Pharmacodynamics

    • Most Recent Events

    • 26 Feb 2024 Planned End Date changed from 31 Mar 2024 to 31 Dec 2025.
    • 26 Feb 2024 Planned primary completion date changed from 31 Dec 2023 to 31 Dec 2025.
    • 24 Feb 2021 Planned End Date changed from 31 Mar 2022 to 31 Mar 2024.

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