Trial Profile

A Phase 1b Trial of Mavorixafor, an Oral CXCR4 Antagonist, in Combination With Ibrutinib in Patients With Waldenstrom's Macroglobulinemia (WM) Whose Tumors Express Mutations in MYD88 and CXCR4

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 29 Aug 2024

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At a glance

Drugs Ibrutinib (Primary) ; Mavorixafor (Primary)
Indications Waldenstrom's macroglobulinaemia
Focus Adverse reactions; Pharmacodynamics; Pharmacokinetics
Sponsors X4 Pharmaceuticals

Most Recent Events

15 Nov 2022 Status changed from active, no longer recruiting to completed.
04 Aug 2022 According to X4 Pharmaceuticals media release, this trial is expected to be completed in the fourth quarter of 2022.
20 Jul 2022 According to X4 Pharmaceuticals media release, additional data expected in early August 2022.

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