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A Phase 1, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCARTCS1 (allogeneic engineered T-cells) in Patients with Relapsed/Refractory Multiple Myeloma (MM)

Trial Profile

A Phase 1, Dose-Escalation and Dose-Expansion Study to Evaluate the Safety, Expansion, Persistence and Clinical Activity of UCARTCS1 (allogeneic engineered T-cells) in Patients with Relapsed/Refractory Multiple Myeloma (MM)

Status: Discontinued
Phase of Trial: Phase I

Latest Information Update: 10 May 2023

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At a glance

  • Drugs UCARTCS 1 (Primary)
  • Indications Multiple myeloma
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Acronyms MELANI-01; MUNDI-01
  • Sponsors Cellectis

Most Recent Events

  • 04 May 2023 Status changed from recruiting to discontinued, according to a Cellectis media release.
  • 04 May 2023 According to a Cellectis media release, To optimize its resources, the Company decided to focus its development efforts on the BALLI-01, AMELI-01 and NATHALI-01 studies and therefore to stop enrollment and treatment of patients in the MELANI-01 study.
  • 03 Mar 2022 According to a Cellectis media release, the company is currently enrolling patients at Dose Level 1 (DL1) with FC preconditioning regimen.

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