Trial Profile

A Phase 1, First-in-Human, Open-Label Study of the Safety, Pharmacokinetics, and Pharmacodynamics of JNJ-67856633, an Inhibitor of MALT1, in Participants With NHL and CLL

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 27 Jun 2025

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At a glance

Drugs Safimaltib (Primary)
Indications B-cell lymphoma; Chronic lymphocytic leukaemia; Diffuse large B cell lymphoma; Non-Hodgkin's lymphoma
Focus Adverse reactions; First in man
Sponsors Janssen Research & Development

Most Recent Events

22 Jun 2025 Status changed from active, no longer recruiting to completed.
03 Feb 2025 Planned End Date changed from 30 Jan 2026 to 30 Apr 2025.
05 Dec 2024 Planned primary completion date changed from 2 Dec 2024 to 30 Apr 2025.

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