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A Randomized Double-Blind, Placebo-controlled Phase II Trial With Safety Run-In of Intramuscular pNGVL4a-Sig/E7(Detox)/HSP70 and TA-CIN for the Treatment of Patients With HPV16+ Atypical Squamous Cells of Undetermined Significance (ASC-US) or Cannot Exclude High Grade SIL (ASC-H) Cytology or Low-grade Squamous Intraepithelial Lesion (LSIL)

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A Randomized Double-Blind, Placebo-controlled Phase II Trial With Safety Run-In of Intramuscular pNGVL4a-Sig/E7(Detox)/HSP70 and TA-CIN for the Treatment of Patients With HPV16+ Atypical Squamous Cells of Undetermined Significance (ASC-US) or Cannot Exclude High Grade SIL (ASC-H) Cytology or Low-grade Squamous Intraepithelial Lesion (LSIL)

Status: Discontinued
Phase of Trial: Phase II

Latest Information Update: 19 Jun 2024

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At a glance

  • Drugs Human papillomavirus vaccine (Primary)
  • Indications Human papillomavirus infections
  • Focus Adverse reactions; Therapeutic Use
  • Acronyms PVX-2
  • Sponsors PAPIVAX

    • Most Recent Events

    • 13 Jun 2024 Status changed from recruiting to discontinued (Slow recruitment/funding).
    • 19 Apr 2022 Planned number of patients changed from 122 to 134.
    • 09 Mar 2021 Planned End Date changed from 30 Dec 2021 to 30 Jan 2024.

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