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Phase 2 Study of ZW25 Plus First-line Combination Chemotherapy in HER2-Expressing Gastrointestinal (GI) Cancers, Including Gastroesophageal Adenocarcinoma (GEA), Biliary Tract Cancer (BTC), and Colorectal Cancer (CRC)

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Phase 2 Study of ZW25 Plus First-line Combination Chemotherapy in HER2-Expressing Gastrointestinal (GI) Cancers, Including Gastroesophageal Adenocarcinoma (GEA), Biliary Tract Cancer (BTC), and Colorectal Cancer (CRC)

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Mar 2025

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At a glance

  • Drugs Zanidatamab (Primary) ; Bevacizumab; Capecitabine; Cisplatin; Fluorouracil; Folinic acid; Gemcitabine; Oxaliplatin; Paclitaxel
  • Indications Adenocarcinoma; Biliary cancer; Cholangiocarcinoma; Colorectal cancer; Gallbladder cancer; Gastric cancer; Gastrointestinal cancer; Oesophageal cancer
  • Focus Adverse reactions; Registrational; Therapeutic Use
  • Sponsors Jazz Pharmaceuticals Inc

    • Most Recent Events

    • 18 Oct 2024 Planned primary completion date changed from 30 Aug 2024 to 31 Jul 2025.
    • 09 Sep 2024 According to Jazz Pharmaceuticals media release, the company will present five abstracts at the European Society for Medical Oncology (ESMO) Congress 2024 from September 13-17, 2024, in Barcelona, Spain.
    • 13 Aug 2024 Planned End Date changed from 30 Oct 2026 to 31 Jul 2025.

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