Trial Profile

A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal Carcinoma FRONTiER Trial

Status: Completed

Phase of Trial: Phase I

Latest Information Update: 06 Jun 2025

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At a glance

Drugs Nivolumab (Primary) ; Cisplatin; Docetaxel; Fluorouracil
Indications Adenosquamous carcinoma; Basal cell cancer; Carcinoma; Oesophageal cancer; Squamous cell cancer
Focus Adverse reactions
Acronyms FRONTiER Trial

Most Recent Events

31 May 2025 Status changed from active, no longer recruiting to completed.
20 Jan 2024 Results assessing primary safety and short-term efficacy for cohort E presented at the 2024 Gastrointestinal Cancers Symposium.
08 Nov 2023 Planned End Date changed from 1 Aug 2023 to 1 Mar 2024.

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