A Phase III Randomized, Placebo-Controlled Study of Pembrolizumab (MK-3475, NSC 776864) in Addition to Paclitaxel and Carboplatin for Measurable Stage III or IVA, Stage IVB or Recurrent Endometrial Cancer
Latest Information Update: 12 Jun 2025
At a glance
- Drugs Pembrolizumab (Primary) ; Carboplatin; Paclitaxel
- Indications Adenocarcinoma; Endometrial cancer
- Focus Registrational; Therapeutic Use
- Acronyms KEYNOTE-868
Most Recent Events
- 06 Jun 2025 Planned End Date changed from 1 Apr 2029 to 8 May 2026.
- 01 May 2025 Results of exploratory analysis assessing efficacy of pembrolizumab plus chemotherapy in advanced or recurrent endometrial cancer published in the Nature Medicine
- 19 Mar 2025 According to Merck and Co media release, company announced that Health Canada approved KEYTRUDA for the treatment of adult patients with primary advanced or recurrent endometrial carcinoma.