Trial Profile

A Phase I Study of the Safety, Pharmacokinetic and Pharmacodynamic Properties of Orally Administered APG-2449 in Patients With Advanced Solid Tumors

Status: Recruiting

Phase of Trial: Phase I

Latest Information Update: 29 Apr 2025

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At a glance

Drugs APG 2449 (Primary)
Indications Brain metastases; Malignant-mesothelioma; Mesothelioma; Non-small cell lung cancer; Oesophageal cancer; Ovarian cancer; Solid tumours
Focus Adverse reactions; First in man
Sponsors Ascentage Pharma

Most Recent Events

24 Apr 2025 Planned number of patients changed from 150 to 165.
26 Feb 2025 Planned End Date changed from 1 Feb 2025 to 1 Jan 2028.
26 Feb 2025 Planned primary completion date changed from 1 Jan 2025 to 1 Dec 2027.

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