Trial Profile

Neoadjuvant Immune Checkpoint Blockade in Resectable Malignant Pleural Mesothelioma

Status: Active, no longer recruiting

Phase of Trial: Phase I/II

Latest Information Update: 12 Jun 2026

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At a glance

Drugs Ipilimumab (Primary) ; Nivolumab (Primary)
Indications Malignant-mesothelioma
Focus Adverse reactions; Therapeutic Use

Most Recent Events

05 Jun 2026 Planned End Date changed from 1 Jun 2027 to 1 Jun 2028.
05 Jun 2026 Planned primary completion date changed from 1 Jun 2026 to 1 Jun 2027.
01 Dec 2025 According to Results presentedin the Nature Medicine, Primary endpoint (Feasibility of neoadjuvant nivolumab +/- ipilimumab in patients with resectable MPM who complete of neoadjuvant treatment and proceed to surgery) has been met.

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