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A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator-controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by Administration of PNEUMOVAX 23 Eight Weeks Later in Children Infected With Human Immunodeficiency Virus (HIV) (PNEU-WAY PED)

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Trial Profile

A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator-controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 Followed by Administration of PNEUMOVAX 23 Eight Weeks Later in Children Infected With Human Immunodeficiency Virus (HIV) (PNEU-WAY PED)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 23 Mar 2023

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At a glance

  • Drugs V 114 (Primary) ; Pneumococcal 13-valent CRM197 vaccine conjugate; Pneumococcal vaccine
  • Indications Pneumococcal infections
  • Focus Adverse reactions; Pharmacodynamics; Registrational
  • Acronyms PNEU-WAY PED
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 20 Mar 2023 Results evaluating the safety and immunogenicity of V114, followed by vaccine PPSV23 in children living with HIV, published in the AIDS
  • 25 Apr 2022 Results presented at the 2022 Annual Meeting of the Pediatric Academic Societies
  • 17 May 2021 Status changed from active, no longer recruiting to completed.

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