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A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase III Study of Pemetrexed + Platinum Chemotherapy With or Without Toripalimab (JS001) in Advanced Non-small Cell Lung Cancer (NSCLC) Participants With TKI-resistant EGFR-mutated Tumors

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Trial Profile

A Randomized, Double-Blind, Placebo-Controlled, Multicenter, Phase III Study of Pemetrexed + Platinum Chemotherapy With or Without Toripalimab (JS001) in Advanced Non-small Cell Lung Cancer (NSCLC) Participants With TKI-resistant EGFR-mutated Tumors

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 10 Aug 2026

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At a glance

  • Drugs Toripalimab (Primary)
  • Indications Non-small cell lung cancer
  • Focus Registrational; Therapeutic Use
  • Sponsors Shanghai Junshi Biosciences

Most Recent Events

  • 06 Aug 2026 Status changed from recruiting to completed.
  • 23 Dec 2022 Planned number of patients changed from 350 to 440.
  • 23 Dec 2022 Planned End Date changed from 1 May 2022 to 8 Aug 2024.

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