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A trial comparing NNC0148-0287 C (insulin 287) versus insulin glargine U100, both in combination with metformin, with or without DPP4 inhibitors and with or without SGLT2 inhibitors, in basal insulin treated subjects with type 2 diabetes mellitus

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Trial Profile

A trial comparing NNC0148-0287 C (insulin 287) versus insulin glargine U100, both in combination with metformin, with or without DPP4 inhibitors and with or without SGLT2 inhibitors, in basal insulin treated subjects with type 2 diabetes mellitus

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 12 Dec 2022

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At a glance

  • Drugs Insulin icodec (Primary) ; Dipeptidyl peptidase 4 inhibitors; Insulin glargine; Metformin; Sodium-glucose transporter 2 inhibitors
  • Indications Type 2 diabetes mellitus
  • Focus Therapeutic Use
  • Acronyms LAI287
  • Sponsors Novo Nordisk

    • Most Recent Events

    • 29 Jun 2021 Results from NCT03951805 and NCT03922750; comapring CGM-derived hypoglycemic episode duration between icodec and IGlar U100 in insulin-naive and insulin-experienced patients with Type-2-diabetes-mellitus, presented at the 81st Annual Scientific Sessions of the American Diabetes Association
    • 29 Jun 2021 Results of a post hoc analysis comparing the time in range, time above range and and below range for icodec (LD and no loading dose - NLD) vs IGlar U100 throughout the 16-week period presented at the 81st Annual Scientific Sessions of the American Diabetes Association
    • 19 Apr 2021 Results published in the Diabetes Care

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