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Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment (ACP-103-054/059)

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Trial Profile

Phase 3, Multicenter, Randomized, Double-blind, Placebo-controlled Study to Evaluate the Efficacy and Safety of Adjunctive Pimavanserin in Subjects With Major Depressive Disorder and Inadequate Response to Antidepressant Treatment (ACP-103-054/059)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 18 Nov 2021

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At a glance

  • Drugs Pimavanserin (Primary)
  • Indications Major depressive disorder
  • Focus Registrational; Therapeutic Use
  • Acronyms CLARITY-2
  • Sponsors Acadia Pharmaceuticals

Most Recent Events

  • 20 Jul 2020 According to an Acadia Pharmaceuticals Media Release, Primary endpoint (Change from Baseline in the Hamilton Depression Scale (17 items) (HAMD-17) total score) has not been met.
  • 20 Jul 2020 Results presented in an Acadia Pharmaceuticals Media Release
  • 22 Jun 2020 Status changed from recruiting to completed.

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