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A Phase 1/2 trial on the safety, tolerability, pharmacokinetics, pharmacodynamics and exploratory efficacy of DYN101 in patients ≥ 16 years of age with centronuclear myopathies caused by mutations in DNM2 or MTM1

Trial Profile

A Phase 1/2 trial on the safety, tolerability, pharmacokinetics, pharmacodynamics and exploratory efficacy of DYN101 in patients ≥ 16 years of age with centronuclear myopathies caused by mutations in DNM2 or MTM1

Status: Discontinued
Phase of Trial: Phase I/II

Latest Information Update: 14 Sep 2023

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At a glance

  • Drugs DYN-101 (Primary)
  • Indications Congenital structural myopathies
  • Focus Adverse reactions; First in man
  • Acronyms Unite-CNM
  • Sponsors Dynacure

Most Recent Events

  • 07 Jul 2022 Status changed from recruiting to discontinued.
  • 07 Jul 2022 This trial has been suspended in Germany and Belgium, according to European Clinical Trials Database record
  • 25 Jun 2022 This trial has been completed in Belgium(End date;2022-06-22), according to European Clinical Trials Database record.

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