Trial Profile

A Phase Ib Trial of Vaginal Cuff Brachytherapy + Pembrolizumab (MK3475) Followed by 3 Cycles of Dose Dense Paclitaxel/q 21 Day Carboplatin + Pembrolizumab (MK3475) in High Intermediate Risk Endometrial Cancer

Status: Active, no longer recruiting

Phase of Trial: Phase I

Latest Information Update: 23 Aug 2025

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At a glance

Drugs Carboplatin (Primary) ; Paclitaxel (Primary) ; Pembrolizumab (Primary)
Indications Carcinoma; Endometrial cancer
Focus Therapeutic Use
Acronyms FIERCE

07 Aug 2025 Planned primary completion date changed from 1 Jul 2025 to 1 Sep 2025.
24 Jul 2025 Planned primary completion date changed from 1 Jun 2025 to 1 Jul 2025.
24 Jul 2025 Status changed from recruiting to active, no longer recruiting.

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