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An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors in Pediatric Participants

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Trial Profile

An Open-Label, Single-Arm, Phase 1/2 Study Evaluating the Safety and Efficacy of Ponatinib for the Treatment of Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors in Pediatric Participants

Status: Recruiting
Phase of Trial: Phase I/II

Latest Information Update: 27 Mar 2025

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At a glance

  • Drugs Ponatinib (Primary)
  • Indications Acute myeloid leukaemia; Chronic myeloid leukaemia; Leukaemia; Lymphoma; Precursor cell lymphoblastic leukaemia-lymphoma; Solid tumours
  • Focus Adverse reactions; Therapeutic Use
  • Sponsors Incyte Biosciences International

Most Recent Events

  • 13 Aug 2024 Planned End Date changed from 4 Jan 2025 to 30 Jan 2026.
  • 13 Aug 2024 Planned primary completion date changed from 7 Dec 2024 to 30 Jan 2026.
  • 12 Sep 2023 Planned number of patients changed from 60 to 85.

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