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A Prospective Phase II, Open-Label, Single-arm, Multicenter, Study to Assess Efficacy and Safety of SEG101 (Crizanlizumab), in Sickle Cell Disease Patients With Priapism (SPARTAN)

Trial Profile

A Prospective Phase II, Open-Label, Single-arm, Multicenter, Study to Assess Efficacy and Safety of SEG101 (Crizanlizumab), in Sickle Cell Disease Patients With Priapism (SPARTAN)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 20 Mar 2025

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At a glance

  • Drugs Crizanlizumab (Primary)
  • Indications Priapism
  • Focus Therapeutic Use
  • Acronyms SPARTAN
  • Sponsors Novartis Pharmaceuticals

Most Recent Events

  • 05 Jan 2024 Status changed from recruiting to completed.
  • 12 Dec 2023 Results (Data cutoff March 28, 2023;n=36)evaluating efficacy and safety of crizanlizumab after 26 weeks of treatment in patients with SCD-related priapism, presented at the 65th American Society of Hematology Annual Meeting and Exposition
  • 15 Jun 2023 Interim results (data cut-off, March 8, 2022, n=24) assessing the efficacy and safety ofcrizanlizumab in SCD patients with priapism presented at the 28th Congress of the European Haematology Association

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