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To assess whether use of a dual P-gp and moderate CYP3A4 inhibitor in combination with rivaroxaban or apixaban increases the risk of bleeding in patients with atrial fibrillation

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Trial Profile

To assess whether use of a dual P-gp and moderate CYP3A4 inhibitor in combination with rivaroxaban or apixaban increases the risk of bleeding in patients with atrial fibrillation

Status: Completed
Phase of Trial: Phase IV

Latest Information Update: 23 Feb 2021

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At a glance

  • Drugs Apixaban (Primary) ; Rivaroxaban (Primary) ; Amiodarone; Diltiazem; Dronedarone; Erythromycin; Verapamil
  • Indications Thromboembolism
  • Focus Adverse reactions

    • Most Recent Events

    • 09 May 2019 New trial record
    • 18 Mar 2019 Results presented at the 68th Annual Scientific Session of the American College of Cardiology

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