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Assessment of Brain O-GlcNAcase (OGA) Enzyme Occupancy After Single Oral Doses of LY3372689 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]LSN3316612 in Healthy Subjects

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Trial Profile

Assessment of Brain O-GlcNAcase (OGA) Enzyme Occupancy After Single Oral Doses of LY3372689 as Measured by Positron Emission Tomography (PET) With the Radioligand [18F]LSN3316612 in Healthy Subjects

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 04 Nov 2021

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At a glance

  • Drugs LY 3372689 (Primary)
  • Indications Unspecified
  • Focus Pharmacodynamics

Most Recent Events

  • 30 Jul 2021 Results from NCT03944031 and NCT04392271 assessing effect of LY3372689 on brain OGA enzyme occupancy, presented at the Alzheimer's Association International Conference 2021
  • 21 Apr 2020 Status changed from recruiting to completed.
  • 18 Feb 2020 Planned End Date changed from 7 Feb 2020 to 6 Mar 2020.

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