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A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (PNEU-SICKLE)

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Trial Profile

A Phase 3, Multicenter, Randomized, Double-blind, Active Comparator Controlled Study to Evaluate the Safety, Tolerability, and Immunogenicity of V114 in Children With Sickle Cell Disease (PNEU-SICKLE)

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 02 Feb 2023

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At a glance

  • Drugs V 114 (Primary) ; Pneumococcal 13-valent CRM197 vaccine conjugate
  • Indications Pneumococcal infections
  • Focus Adverse reactions; Pharmacodynamics; Registrational
  • Acronyms PNEU-SICKLE
  • Sponsors Merck Sharp & Dohme Corp.

Most Recent Events

  • 25 Apr 2022 Results presented at the 2022 Annual Meeting of the Pediatric Academic Societies
  • 30 Jun 2020 Status changed from active, no longer recruiting to completed.
  • 29 Jan 2020 Planned End Date changed from 27 Aug 2020 to 29 Jun 2020.

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