Trial Profile

A Phase 1b/2a, Open-Label, Dose-Exploration Basket Study to Investigate the Safety and Tolerability of Subretinally Injected OPGx-BEST1 Administered in Patients With Either Autosomal-Dominant BEST1 Disease (Best Vitelliform Macular Dystrophy [BVMD]) or Autosomal-Recessive Bestrophinopathy (ARB)

Status: Recruiting

Phase of Trial: Phase I/II

Latest Information Update: 10 Mar 2026

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At a glance

27 Feb 2026 According to an Opus Genetics media release, Two participants have been enrolled to date, with 3-month results from the full Cohort 1 expected in mid-year 2026.
27 Feb 2026 According to an Opus Genetics media release, data from this trial was presented at the 49th Annual Meeting of the Macula Society, in San Diego, California.
27 Feb 2026 Results presented in the Opus Genetics media release.

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