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Phase 2, multicenter, randomized, open-label, controlled, 2-arm cross-over study to evaluate the clinical efficacy and safety of a renin inhibitor, aliskiren, compared to an angiotensin converting enzyme inhibitor, enalapril, in children and adults with C3 glomerulopathy

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Phase 2, multicenter, randomized, open-label, controlled, 2-arm cross-over study to evaluate the clinical efficacy and safety of a renin inhibitor, aliskiren, compared to an angiotensin converting enzyme inhibitor, enalapril, in children and adults with C3 glomerulopathy

Status: Recruiting
Phase of Trial: Phase II

Latest Information Update: 15 Jul 2024

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At a glance

  • Drugs Aliskiren (Primary) ; Enalapril
  • Indications Membranoproliferative glomerulonephritis
  • Focus Therapeutic Use
  • Acronyms Reninblock-C3G

    • Most Recent Events

    • 17 Jun 2024 Planned End Date changed from 1 Dec 2024 to 1 Dec 2029.
    • 17 Jun 2024 Planned primary completion date changed from 1 Dec 2024 to 1 Dec 2029.
    • 25 Mar 2020 Status has been changed to recruiting.

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