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An Open-label, Single-Sequence, 2-Treatment Period Study to Investigate the Effects of Cytochrome P450 3A4 Inhibition by Itraconazole on the Pharmacokinetics of BMS-986256 in Healthy Participants

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Trial Profile

An Open-label, Single-Sequence, 2-Treatment Period Study to Investigate the Effects of Cytochrome P450 3A4 Inhibition by Itraconazole on the Pharmacokinetics of BMS-986256 in Healthy Participants

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Apr 2022

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At a glance

  • Drugs Afimetoran (Primary) ; Itraconazole
  • Indications Autoimmune disorders; Cutaneous lupus erythematosus; Systemic lupus erythematosus
  • Focus Pharmacokinetics
  • Sponsors Bristol-Myers Squibb

Most Recent Events

  • 18 Mar 2022 Results assessing impact of itraconazole on PK of BMS-986256, presented at the 123rd Annual Meeting of the American Society for Clinical Pharmacology and Therapeutics.
  • 25 Oct 2019 Status changed from recruiting to completed.
  • 12 Aug 2019 Planned number of patients changed from 24 to 45.

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