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A Phase 2b Multicenter Dose-Ranging Study Evaluating the Safety and Efficacy of Sunitinib Malate Depot Formulation (GB-102) Compared to Aflibercept in Subjects With Neovascular (Wet) Age-related Macular Degeneration (ALTISSIMO Study)

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Trial Profile

A Phase 2b Multicenter Dose-Ranging Study Evaluating the Safety and Efficacy of Sunitinib Malate Depot Formulation (GB-102) Compared to Aflibercept in Subjects With Neovascular (Wet) Age-related Macular Degeneration (ALTISSIMO Study)

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Aug 2022

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At a glance

  • Drugs Sunitinib (Primary) ; Aflibercept
  • Indications Wet age-related macular degeneration
  • Focus Therapeutic Use
  • Acronyms ALTISSIMO
  • Sponsors GrayBug inc.
  • Most Recent Events

    • 11 Aug 2022 According to a GrayBug inc media release, clinical trial expense decreased due to the completion of the extension phase of this trial in May 2021, this decrease was largely offset by an increase in non-clinical outside expense related to the GB-401 program and an increase in consulting fees related to the GB-501 program.
    • 03 Feb 2022 According to a GrayBug inc media release, data from this study will be presented at Angiogenesis, Exudation, and Degeneration 2022, Virtual Edition, on February 11, 2022, data will be discuss by dr. Veeral Sheth.
    • 01 Nov 2021 According to a GrayBug inc. media release, data from this study will be presented as a company's presentation at the Eyecelerator @ AAO 2021 event on November 11, 2021.

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