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A Multi-Center, Randomized, Double-blind, Placebo-controlled, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Symptomatic Hypertrophic Cardiomyopathy

Trial Profile

A Multi-Center, Randomized, Double-blind, Placebo-controlled, Dose-finding Study to Evaluate the Safety, Tolerability, Pharmacokinetics, and Pharmacodynamics of CK-3773274 in Adults With Symptomatic Hypertrophic Cardiomyopathy

Status: Completed
Phase of Trial: Phase II

Latest Information Update: 19 Mar 2025

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At a glance

  • Drugs Aficamten (Primary) ; Disopyramide
  • Indications Hypertrophic cardiomyopathy
  • Focus Adverse reactions
  • Acronyms REDWOOD-HCM; REDWOOD-HCM
  • Sponsors Cytokinetics

Most Recent Events

  • 17 Mar 2025 Results presented in the Cytokinetics Media Release.
  • 17 Mar 2025 According to a Cytokinetics media release, data from this study will be presented at the American College of Cardiology (ACC) Annual Scientific Session & Expo taking place from March 29, 2025-March 31, 2025 in Chicago, IL.
  • 01 Nov 2024 Results assessing safety and efficacy of aficamten in patients with nonobstructive hypertrophic cardiomyopathy , published in the Journal of Cardiac Failure.

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