Trial Profile

Sanaria PfSPZ Challenge With Pyrimethamine or Chloroquine Chemoprophylaxis Vaccination (PfSPZ-CVac Approach): A Randomized Double Blind Placebo Controlled Phase I/II Trial to Determine Safety and Protective Efficacy Against Natural Plasmodium Falciparum Infection in Bancoumana and Surrounding Areas, Mali

Status: Completed

Phase of Trial: Phase I/II

Latest Information Update: 13 Jul 2022

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At a glance

Drugs Malaria vaccine live unattenuated-Sanaria (Primary) ; Antimalarials; Artemether/lumefantrine; Chloroquine diphosphate; Ibuprofen; Pyrimethamine
Indications Falciparum malaria
Focus Adverse reactions

09 Jul 2021 Status changed from recruiting to completed.
15 Apr 2021 Planned End Date changed from 30 Apr 2021 to 30 Apr 2023.
15 Apr 2021 Planned primary completion date changed from 30 Apr 2021 to 30 Sep 2022.

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