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The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. A Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

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Trial Profile

The PRIME Trial: PARP Inhibition in IDH Mutant Effectiveness Trial. A Phase II Study of Olaparib in Isocitrate Dehydrogenase (IDH) Mutant Relapsed/Refractory Acute Myeloid Leukemia and Myelodysplastic Syndrome

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 21 Apr 2025

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At a glance

  • Drugs Olaparib (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Biomarker; Proof of concept; Therapeutic Use
  • Acronyms PRIME

Most Recent Events

  • 30 Mar 2025 Planned End Date changed from 8 Nov 2025 to 20 Feb 2026.
  • 12 Nov 2024 Planned End Date changed from 1 Dec 2024 to 8 Nov 2025.
  • 05 Dec 2023 Planned End Date changed from 1 Dec 2023 to 1 Dec 2024.

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