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A First-in-Human Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of JNJ-74699157 in Participants With Advanced Solid Tumors Harboring the KRAS G12C Mutation

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Trial Profile

A First-in-Human Study of the Safety, Pharmacokinetics, Pharmacodynamics, and Preliminary Antitumor Activity of JNJ-74699157 in Participants With Advanced Solid Tumors Harboring the KRAS G12C Mutation

Status: Completed
Phase of Trial: Phase I

Latest Information Update: 21 Jul 2022

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At a glance

  • Drugs ARS 3248 (Primary)
  • Indications Colorectal cancer; Non-small cell lung cancer; Solid tumours
  • Focus Adverse reactions; First in man; Therapeutic Use
  • Sponsors Janssen Biotech; Janssen Research & Development

Most Recent Events

  • 05 Jul 2022 Results published in the Oncologist
  • 14 Sep 2020 Status changed from active, no longer recruiting to completed.
  • 02 Jun 2020 Planned End Date changed from 6 Jul 2023 to 3 Mar 2021.

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