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A Phase 3, Placebo-controlled, Double-blind Comparative Study of KHK4827 With an Open-label Extension Period in Subjects With Systemic Sclerosis Who Have Moderate to Severe Skin Thickening

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Trial Profile

A Phase 3, Placebo-controlled, Double-blind Comparative Study of KHK4827 With an Open-label Extension Period in Subjects With Systemic Sclerosis Who Have Moderate to Severe Skin Thickening

Status: Completed
Phase of Trial: Phase III

Latest Information Update: 23 Jul 2025

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At a glance

  • Drugs Brodalumab (Primary)
  • Indications Diffuse scleroderma; Systemic scleroderma
  • Focus Registrational; Therapeutic Use
  • Sponsors Kyowa Kirin

Most Recent Events

  • 11 Jul 2025 Status changed from active, no longer recruiting to completed.
  • 24 Dec 2024 Planned End Date changed from 28 Feb 2025 to 1 Apr 2025.
  • 16 Jul 2024 Planned End Date changed from 29 Feb 2024 to 28 Feb 2025.

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