Trial Profile

Genomically-Guided Treatment Trial in Brain Metastases

Status: Suspended

Phase of Trial: Phase II

Latest Information Update: 09 Jan 2026

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At a glance

Drugs Abemaciclib (Primary) ; Entrectinib (Primary) ; Paxalisib (Primary)
Indications Advanced breast cancer; Brain metastases; HER2 negative breast cancer; HER2 positive breast cancer; Lung cancer; Malignant melanoma; Solid tumours
Focus Therapeutic Use

Most Recent Events

08 Sep 2025 Status changed from recruiting to suspended.
15 Jan 2025 Planned End Date changed from 1 Jun 2026 to 1 Jun 2028.
15 Jan 2025 Planned primary completion date changed from 1 Oct 2025 to 1 Oct 2026.

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