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A Dose-Escalation, Open Label Phase I Study to Assess the Safety, Feasibility and Preliminary Efficacy of HA-1H TCR Modified T Cells, MDG1021, in Patients With Relapsed or Persistent Hematologic Malignancies After Allogeneic HSCT With or Without Unmanipulated DLI

Trial Profile

A Dose-Escalation, Open Label Phase I Study to Assess the Safety, Feasibility and Preliminary Efficacy of HA-1H TCR Modified T Cells, MDG1021, in Patients With Relapsed or Persistent Hematologic Malignancies After Allogeneic HSCT With or Without Unmanipulated DLI

Status: Withdrawn prior to enrolment
Phase of Trial: Phase I

Latest Information Update: 13 Oct 2021

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At a glance

  • Drugs MDG 1021 (Primary)
  • Indications Acute myeloid leukaemia; B-cell lymphoma; Chronic myeloid leukaemia; Haematological malignancies; Multiple myeloma; Mycosis fungoides; Myelodysplastic syndromes; Myeloproliferative disorders; Precursor cell lymphoblastic leukaemia-lymphoma; T-cell lymphoma
  • Focus Adverse reactions
  • Sponsors MediGene AG

Most Recent Events

  • 30 Sep 2021 Planned End Date changed from 1 Jan 2024 to 1 Jul 2025.
  • 30 Sep 2021 Status changed from active, no longer recruiting to withdrawn prior to enrolment because Medigene transfered all rights to a new Sponsor.
  • 01 Feb 2021 Status changed from suspended to active, no longer recruiting.

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