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A Phase 2 Open-Label Study of Sacituzumab Govitecan (IMMU-132) in Subjects With Metastatic Solid Tumors

Trial Profile

A Phase 2 Open-Label Study of Sacituzumab Govitecan (IMMU-132) in Subjects With Metastatic Solid Tumors

Status: Active, no longer recruiting
Phase of Trial: Phase II

Latest Information Update: 06 Mar 2025

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At a glance

  • Drugs Sacituzumab govitecan (Primary)
  • Indications Adenocarcinoma; Advanced breast cancer; Carcinoma; Endometrial cancer; Head and neck cancer; Non-small cell lung cancer; Small cell lung cancer; Solid tumours; Squamous cell cancer; Urogenital cancer
  • Focus Proof of concept; Therapeutic Use
  • Acronyms Tropics-03
  • Sponsors Gilead Sciences; Immunomedics

Most Recent Events

  • 03 Mar 2025 Planned End Date changed from 1 Mar 2025 to 1 Sep 2025.
  • 17 Dec 2024 According to Gilead Sciences media release, based on result form this trial, the U.S. Food and Drug Administration (FDA) has granted Breakthrough Therapy Designation to Trodelvy (sacituzumab govitecan-hziy) for the treatment of adult patients with extensive-stage small cell lung cancer (ES-SCLC) whose disease has progressed on or after platinum-based chemotherapy.
  • 05 Sep 2024 According to Gilead Sciences media release, company will present updated results from the global Phase 2 TROPiCS-03 ES-SCLC Cohort during the IASLC 2024 World Conference on Lung Cancer hosted by the International Association for the Study of Lung Cancer, taking place Sept. 7-10, 2024 in San Diego, Calif.

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