Trial Profile

A Phase 2 Study of MLN4924 (Pevonedistat) in Combination With Carboplatin and Paclitaxel in Advanced NSCLC Previously Treated With Immunotherapy

Status: Active, no longer recruiting

Phase of Trial: Phase II

Latest Information Update: 10 Apr 2025

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At a glance

Drugs Carboplatin (Primary) ; Paclitaxel (Primary) ; Pevonedistat (Primary)
Indications Non-small cell lung cancer
Focus Therapeutic Use

Most Recent Events

06 Apr 2025 Planned End Date changed from 20 Mar 2025 to 18 Mar 2026.
21 Mar 2024 Planned End Date changed from 9 Mar 2024 to 20 Mar 2025.
11 Dec 2023 Time frame for primary end-point is reduced from 5 years to 2.5 years.

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