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Phase 1b Study of Pembrolizumab, Decitabine +/- Venetoclax Combination Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

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Trial Profile

Phase 1b Study of Pembrolizumab, Decitabine +/- Venetoclax Combination Therapy in Patients With Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome

Status: Recruiting
Phase of Trial: Phase I

Latest Information Update: 18 Mar 2026

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At a glance

  • Drugs Decitabine (Primary) ; Pembrolizumab (Primary)
  • Indications Acute myeloid leukaemia; Myelodysplastic syndromes
  • Focus Adverse reactions; Therapeutic Use

Most Recent Events

  • 05 Mar 2026 Planned End Date changed from 10 Feb 2026 to 4 Jul 2027.
  • 05 Mar 2026 Planned primary completion date changed from 10 Feb 2026 to 4 Jul 2027.
  • 05 Dec 2025 Planned End Date changed from 4 Nov 2025 to 10 Feb 2026.

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